J Vet Sci. 2005 Jun;6(2):165-167   
 

Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F2メ closely before parturition

Norio Yamagishi1,*, Yu Ayukawa2, Inhyung Lee3, Kenji Oboshi1, Yoshihisa Naito4

 

1Research Center for Animal Hygiene and Food Safety, and 2Department of Veterinary Clinical Sciences, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan. 3Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1069, USA. 4Department of Veterinary Clinical Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate 020-8550, Japan.

 

To determine the effect of exogenous 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] combined with induced parturition on calcium (Ca) metabolism, cows received a single intramuscular injection of 1,25(OH)2D3 and prostaglandin F2メ (PGF2メ) closely before calving. Ten late-pregnant, multiparous Holstein cows were assigned to 1,25(OH)2D3 group (five treated with both 1,25(OH)2D3 and PGF2メ) and control group (five treated with PGF2メ). 1,25(OH)2D3 group showed an increase in plasma Ca concentration around parturition, whereas control group revealed a decrease in plasma Ca level. Plasma Ca concentration in 1,25(OH)2D3 group were significantly higher than that in control group during .0.5 to 3 days after parturition.