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J Vet Sci. 2005 Sep;6(3):243-245 |
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Successful surgical correction of anal atresia in a transgenic cloned piglet
Gab Sang
Lee1,
Hye Soo Kim1,
So Hyun
Lee1,
Dae Yong Kim3,4,
Kang
Moon Seo5,
Sang Hwan
Hyun6,
Sung Keun
Kang1,3,4,
Byeong Chun
Lee1,3,4*,
Woo Suk Hwang
1,2,3 |
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1Department of Theriogenology and
Biotechnology, College of Veterinary Medicine, Seoul National
University, Seoul 151-742, Korea. bclee@snu.ac.kr.
2 Department of Pathology, College of Veterinary
Medicine, Seoul National University, Seoul 151-742, Korea.
3 Department of Surgery, College of Veterinary
Medicine, Seoul National University, Seoul 151-742, Korea.
4 School of Agricultural Biotechnology, Seoul National
University, Seoul 151-742, Korea.
5 Xenotransplantation Research Center,
Seoul National University Hospital, Seoul 110-744, Korea.
6Department of Veterinary Biotechnology, College of Veterinary
Medicine, Chungbuk National University, Cheongju 361-763,
Korea. |
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Inbred strains of pig become indispensable for a wide range of biological studies. In biomedical science, it is generally accepted that somatic cell nuclear transfer(SCNT)technology with inbreed strain of pig is essential for xenotransplantation. In this study, we observed the anal atresia in a cloned pig which was derived from fetal fibroblast of inbreed miniature pig. A presumptive anal site of the cloned pig was excised and the rectum was sutured to apposed skin for treatment. This cloned piglet seemed to be normal with healthy status after surgery. This report can be useful for the treatment of anal atresia of cloned piglets. |
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