J Vet Sci. 2007 Dec;8(4):423-425   
 

Mammary fibroadenoma in a lamb

M. Yavuz Gulbahar1,*, Tolga Guvenc1, Murat Yarim1, Yonca B. Kabak1, Yuksel Sozgen2

 

1Department of Pathology, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55139 Kurupelit, Samsun, Turkey
2Veterinary Provincial Directorate, 20770 Baklan, Denizli, Turkey

* mygulbahar@hotmail.com

 

A fibroadenoma was diagnosed in the left udder of a 3-month-old female Chios lamb. No recurrence was observed after surgery. Grossly, the tumor had a whitishgray lobular appearance, and the lobules were interlaced with thin septa. Microscopically, the tumor was composed of proliferating fibroepithelial tissue, including differentiated ducts lined by whorls and interlacing bundles of abundant loose fibrovascular stroma. Immunohistochemistry revealed the ductal epithelium to be positive for pancytokeratin (AE1/AE3) and loose fibrovascular stroma was positive for vimentin and basal cells covering the ductal epithelium of alpha-smooth-muscle actin. Immunostaining for the estrogen and progesterone receptors was negative. A diagnosis of mammary fibroadenoma was made based on the histological and immunohistochemical findings.