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J Vet Sci. 2007 Dec;8(4):423-425 |
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Mammary fibroadenoma in a lamb
M. Yavuz Gulbahar1,*, Tolga Guvenc1, Murat Yarim1, Yonca B. Kabak1, Yuksel Sozgen2 |
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1Department of Pathology, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55139 Kurupelit, Samsun, Turkey
2Veterinary Provincial Directorate, 20770 Baklan, Denizli, Turkey
* mygulbahar@hotmail.com |
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A fibroadenoma was diagnosed in the left udder of a
3-month-old female Chios lamb. No recurrence was observed
after surgery. Grossly, the tumor had a whitishgray
lobular appearance, and the lobules were interlaced
with thin septa. Microscopically, the tumor was composed
of proliferating fibroepithelial tissue, including differentiated
ducts lined by whorls and interlacing bundles of
abundant loose fibrovascular stroma. Immunohistochemistry
revealed the ductal epithelium to be positive for pancytokeratin
(AE1/AE3) and loose fibrovascular stroma
was positive for vimentin and basal cells covering the ductal
epithelium of alpha-smooth-muscle actin. Immunostaining
for the estrogen and progesterone receptors was
negative. A diagnosis of mammary fibroadenoma was
made based on the histological and immunohistochemical
findings.
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