Histopathologic findings in uterus and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: a cross-sectional Study
Daniel Maya-Pulgarin1, Mar?a S. Gonzalez-Dominguez1,2, Diego Aranzazu-Taborda3,4, Natalia Mendoza1, Juan G. Maldonado-Estrada3,*
1Grupo de Investigaci?n INCA-CES, Facultad de Medicina Veterinaria y Zootecnia, Universidad CES, Calle 10 # 22-04, Medell?n, Colombia
2Centro de Medicina Veterinaria y Zootecnia, Universidad CES. Km 4 via el Escobero. Envigado, Colombia
3Grupo de Investigaci?n en Ciencias Veterinarias Centauro, Escuela de Medicina Veterinaria, Facultad de Ciencias Agrarias, Carrera 75 # 65-87, Universidad de Antioquia, Medell?n, Colombia
4Laboratorio de Patolog?a Animal, Escuela de Medicina Veterinaria, Facultad de Ciencias Agrarias, Carrera 75 # 65-87, Universidad de Antioquia, Medell?n, Colombia
Correspondence to: Tel: +573104175926; Fax: +5742199104; E-mail: juan.maldonado@udea.edu.co
Received: November 13, 2015; Revised: May 5, 2016; Accepted: July 21, 2016; Published online: August 10, 2016.
Abstract
Ovariohysterectomy (OHE) of bitches is a matter of conflict depending on the region and country in the world. In a descriptive, prospective cross-sectional study uterine tracts and ovaries exhibiting gross pathologic findings (n = 76) were collected post-surgery from a reference population of 3600 bitches (2,11% incidence) undergoing elective ovariohysterectomy during the warm-humid season (September-to-November 2013, average 26ºC) and were evaluated by histopathology examination. Data were evaluated by descriptive statistics and Chi-Squared test. Bitches were of crossbred background, averaged 5 years (Range 0.6 to 8.0 years), and most were nulliparous (67.9%) with no anamnesis of reproductive diseases (85%). Frequency of proestrus, estrus, and diestrus was 59, 25.5, and 9.0%, respectively. It was found 5.26% of mammary gland masses significantly correlated with age and ovarian histopathologic findings (P<0.05). Predominant histopathology of uterus included cystic endometrial hyperplasia, periglandular fibrosis, lymphoplasmocytary endometritis and adenomyosis (19.74, 14.47, 4 and 2.63%, respectively). In ovaries they were hyperplasia of rete ovarii, follicular cysts, oophoritis, adenoma of the rete ovarii, cysts of superficial structures and granulose-cell tumor (10.5, 6.58, 6.58 3.95, 2.6, and 2.63%, respectively). These results evidenced the incidence of subclinical pathologies in healthy bitches suggesting that OHE at early age is beneficial for its prevention.
Keywords: canine neoplastic disease, canine ovarian pathology, canine uterine pathology, cystic endometrial hyperplasia.


© 2016 The Korean Society of Veterinary Science.