• home
  • articles
  • authors
  • Reviewers
  • About the Journal
  • About the Journal
  • About the Journal
  • About the Journal
  • About the Journal
  • e-Submission

Indexed/Covered by

Seroprevalence of three influenza A viruses (H1N1, H3N2, and H3N8) in pet dogs presented to veterinary hospital in Ohio
Hyesun Jang1,2, Yasmine K. Jackson3, Joshua B. Daniels4, Ahmed Ali1,†, Kyung-il Kang1, Mohamed Elaish1,2, Chang-Won Lee1,2,*,†
1Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Wooster, OH
2Department of Veterinary Preventive Medicine
3Department of Animal Sciences
4Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, OH

Correspondence to: Tel: +330-263-3750; Fax: +330-263-3677; E-mail: lee.2854@osu.edu
Current address: Department of Poultry Diseases, Beni-Suef University, Beni-Suef, Egypt.
Received: January 18, 2016; Revised: May 24, 2016; Accepted: July 21, 2016; Published online: August 10, 2016.
Abstract
The prevalence of canine H3N8 influenza, and human H1N1 and H3N2 influenza in dogs in Ohio was estimated by conducting serologic tests on 1,082 canine serum samples; risk factors, such as health status and age were examined. The prevalence of human H1N1, H3N2, and canine H3N8 were 4.0%, 2.4% and 2.3%, respectively, and two samples were seropositive to two subtypes (H1N1 and H3N2; H1N1 and canine influenza virus (CIV) H3N8). Dogs with respiratory signs were 5.795 times more likely to be seropositive against human H1N1 virus than healthy dogs (p-value=0.042). The prevalence of human flu infection increased in accordance with the increase in age and varied by the serum collection month. A commercial ELISA used in this study could not detect nucleoprotein specific antibodies from many HI positive sera, which indicates the need for the development and validation of rapid tests for influenza screening in canine population. In summary, we confirmed low exposure of dogs to CIV and human influenza viruses in Ohio. We identified potential risk factors involved for consideration in future investigations. Our findings also support the need for establishment of reliable diagnostic standards for serologic detection of influenza infection in canine species.
Keywords: Canine influenza, Serology, Risk factors, Prevalence, Cross-sectional study


© 2016 The Korean Society of Veterinary Science.