J. Vet. Sci. 2016; 17(4): 515-521  https://doi.org/10.4142/jvs.2016.17.4.515
Post-pandemic seroprevalence of human influenza viruses in domestic cats
Mahmoud Ibrahim1,3,†, Ahmed Ali1,4,†, Joshua B. Daniels2, Chang-Won Lee1,5,*
1Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA
Departments of 2Veterinary Clinical Science, and 5Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA
3Department of Birds and Rabbit Medicine, Faculty of Veterinary Medicine, University of Sadat City, Menoufiya 32897, Egypt
4Department of Poultry Diseases, Faculty of Veterinary Medicine, Beni-Suef University, Beni Suef 62511, Egypt
Correspondence to: Chang-Won Lee
Tel: +1-330-263-3750; Fax: +1-330-263-3677;
E-mail: lee.2854@osu.edu
Received: December 24, 2015; Revised: January 22, 2016; Accepted: March 4, 2016; Published online: December 30, 2016.
Abstract
The continuous exposure of cats to diverse influenza viruses raises the concern of a potential role of cats in the epidemiology of these viruses. Our previous seroprevalence study of domestic cat sera collected during the 2009 H1N1 pandemic wave (September 2009?September 2010) revealed a high prevalence of pandemic H1N1, as well as seasonal H1N1 and H3N2 human flu virus infection (22.5%, 33.0%, and 43.5%, respectively). In this study, we extended the serosurvey of influenza viruses in cat sera collected post-pandemic (June 2011?August 2012). A total of 432 cat sera were tested using the hemagglutination inhibition assay. The results showed an increase in pandemic H1N1 prevalence (33.6%) and a significant reduction in both seasonal H1N1 and H3N2 prevalence (10.9% and 17.6%, respectively) compared to our previous survey conducted during the pandemic wave. The pandemic H1N1 prevalence in cats showed an irregular seasonality pattern in the post-pandemic phase. Pandemic H1N1 reactivity was more frequent among female cats than male cats. In contrast to our earlier finding, no significant association between clinical respiratory disease and influenza virus infection was observed. Our study highlights a high susceptibility among cats to human influenza virus infection that is correlated with influenza prevalence in the human population.
Keywords: H1N1 subtype, cats, influenza A virus, pandemics, seroepidemiologic studies


© 2016 The Korean Society of Veterinary Science.