A retrospective study of degenerative mitral valve disease in small-breed dogs: Survival and prognostic variables
Hyun-Tae Kim1,†, Sei-Myoung Han1,†, Woo-Jin Song1, Boeun Kim2, Mincheol Choi2, Junghee Yoon2, Hwa-Young Youn1,*
Departments of 1Veterinary Internal Medicine, and 2Veterinary Medical Imaging, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
Correspondence to: Tel: +82-2-880-1266; Fax: +82-2-876-8662; E-mail: hyyoun@snu.ac.kr
The first two authors contributed equally to this work.
Received: December 22, 2015; Revised: August 31, 2016; Accepted: November 23, 2016; Published online: January 4, 2017.
Small-breed (n= 168 dogs; weight < 15 kg) diagnosed with MMVD based on a routine clinical examination, radiology, an electrocardiogram, and echocardiography at the Seoul National University Veterinary Medical Teaching Hospital were included. The survival periods were ascertained and a significant difference was observed in the survival rates between the International Small Animal Cardiac Health Council classes. The mean follow-up period was 14.3 ± 12.1 months. Univariate analysis revealed that dyspnea, pulmonary edema, and vertebral heart score were significantly associated with the survival times (P < 0.05). Additionally, age, left atrial-to-aortic root ratio, ejection fraction, and left ventricular end diastolic volume were associated with increased risk of death (P < 0.1), while body weight, body condition score, systolic blood pressure, arrhythmia, syncope, fractional shortening, and end systolic volume were not associated with the risk of death. These results suggest that, among the variables, dyspnea, pulmonary edema, and vertebral heart score could be useful prognostic factors when giving information about patients to owners.
Keywords: congestive heart failure, mitral valve disease, prognosis, survival rate, vertebral heart score

© 2017 The Korean Society of Veterinary Science.