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Clinical application of quantitative computed tomography in osteogenesis imperfecta suspected cat
Sungjun Won1,3, Woo-jo Chung2, Junghee Yoon3,*
1Irion Animal Hospital, Seoul 06015, Korea
2Ray Veterinary Medical Center, Seoul 06280, Korea
3College of Veterinary Medicine and the Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea
Correspondence to: Tel: +82-2-880-1265; Fax: +82-2-876-8662; E-mail: heeyoon@snu.ac.kr
Received: June 2, 2016; Revised: October 4, 2016; Accepted: November 23, 2016; Published online: January 4, 2017.
One year-old male Persian cat was presented with multiple fractures without known traumatic history. Marked decrease of bone radiopacity and thin cortices of all long bones were identified in radiography. Tentative diagnosis was osteogenesis imperfecta, which is congenital disorder characterized with fragile bone. To identify bone material density (BMD), quantitative computed tomography (QCT) was performed. With QCT, mean trabecular BMD of vertebral bodies was 149.9 ± 86.5 mg/cm3. After bisphosphonate therapy, BMD of same site was 218.5 ± 117.1 mg/cm3, which has been increased significantly (p<0.05). QCT was useful diagnostic tool to diagnose osteopenia and quantify response to medical treatment.
Keywords: cat, osteogenesis imperfecta, osteopenia, quantitative computed tomography

© 2017 The Korean Society of Veterinary Science.