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Guanosine 5′-monophosphate-chelated calcium and iron feed additives maintains egg production and prevents Salmonella Gallinarum in experimentally infected layers
Hye-Ji Noh1, HeeKyong Kim1, Su Jeong Heo2, Hyang Hyun Cho1, Hong Bum Koh2,*
1Medinutrol Co., Ltd., Yeonggwang 57024, Korea
2College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Korea
Correspondence to: Tel: +82-62-530-2849; Fax: +82-62-530-2809; E-mail: hbkoh@chonnam.ac.kr
Received: August 24, 2016; Revised: September 12, 2016; Accepted: November 23, 2016; Published online: January 4, 2017.
We evaluated the effects of guanosine 5′-monophosphate (GMP) -chelated calcium and iron (CaFe-GMP) on the health and egg quality in layers experimentally infected with Salmonella Gallinarum. In this study, CaFe-GMP feed additives was fed with commercial layer feed to layer over four weeks and all were inoculated with Salmonella Gallinarum. Body weight, mortality, clinical symptoms, and poultry production including feed intake, egg production, egg loss, and feed conversion rate were observed and Salmonella Gallinarum was re-isolated from the liver, spleen, and cecum of the layers. All tested internal organs for the CaFe-GMP additive group exhibited significantly lower re-isolation numbers of Salmonella Gallinarum and less severe pathological changes than the control group, indicating that the CaFe-GMP additive feed supplement induced bacterial clearance and increased resistance to Salmonella Gallinarum. Additionally, the CaFe-GMP additive group exhibited better egg production, including higher laying rate and fewer broken eggs, because of inhibitory action on the growth of Salmonella Gallinarum. 0.16% CaFe-GMP may provide a solution for the prevent of salmonellosis in the poultry industry.
Keywords: Salmonella Gallinarum, feed additives, layer, organic mineral

© 2017 The Korean Society of Veterinary Science.