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J Vet Sci 2017; 18(3): 369-376  https://doi.org/10.4142/jvs.2017.18.3.369
Retrospective study of degenerative mitral valve disease in small-breed dogs: survival and prognostic variables
Hyun-Tae Kim1,†, Sei-Myoung Han1,†, Woo-Jin Song1, Boeun Kim2, Mincheol Choi2, Junghee Yoon2, Hwa-Young Youn1,*
Departments of 1Veterinary Internal Medicine, and 2Veterinary Medical Imaging, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea
Correspondence to: Hwa-Young Youn
Tel: +82-2-880-1266; Fax: +82-2-876-8662; E-mail: hyyoun@snu.ac.kr
Received: December 22, 2015; Revised: August 31, 2016; Accepted: November 23, 2016; Published online: September 30, 2017.
Abstract
Small-breed dogs (n = 168; weight < 15 kg) diagnosed with myxomatous mitral valve degeneration based on a routine clinical examination, radiology, electrocardiography, and echocardiography at the Seoul National University Veterinary Medical Teaching Hospital were included in this study. Survival periods were determined, and there were significant differences in survival rates among the three International Small Animal Cardiac Health Council classes. The mean follow-up period was 14.3 ± 12.1 months. Univariate analysis revealed that dyspnea, pulmonary edema, and vertebral heart score were significantly associated with survival time (p < 0.05). Additionally, age, left atrial-to-aortic root ratio, ejection fraction, and left ventricular end diastolic volume were associated with an increased risk of death (p < 0.1), while body weight, body condition score, systolic blood pressure, arrhythmia, syncope, fractional shortening, and end systolic volume were not associated with an increased risk of death. These results suggest that among the assessed variables dyspnea, pulmonary edema, and vertebral heart score could be useful prognostic factors for providing patient information to owners.
Keywords: congestive heart failure, mitral valve disease, prognosis, survival rate, vertebral heart score


© 2017 The Korean Society of Veterinary Science.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.