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J Vet Sci 2017; 18(3): 407-414  https://doi.org/10.4142/jvs.2017.18.3.407
Histopathologic findings in uteri and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: a cross-sectional study
Daniel Maya-Pulgarin1, María Soledad Gonzalez-Dominguez1,2, Diego Aranzazu-Taborda3,4, Natalia Mendoza1, Juan Guillermo Maldonado-Estrada3,*
1INCA-CES Research Group, School of Veterinary Medicine and Zootechny, CES University, Medellin 050021, Colombia
2Veterinary Teaching Hospital, CES University, Envigado 0555427, Colombia
3Research Group on Veterinary Sciences Centauro and 4Laboratory of Veterinary Pathology, School of Veterinary Medicine, Faculty of Agrarian Sciences, University of Antioquia, Medellin 050010, Colombia
Correspondence to: Juan Guillermo Maldonado-Estrada
Tel: +57-3175388397; Fax: +57-42199104; E-mail: juan.maldonado@udea.edu.co
Received: November 13, 2015; Revised: May 5, 2016; Accepted: July 21, 2016; Published online: September 30, 2017.
Opinions on ovariohysterectomy (OHE) of bitches vary depending on region and country. In this descriptive, prospective cross-sectional study, uterine tracts and ovaries exhibiting gross pathologic findings (n = 76) were collected post-surgery from a reference population of 3,600 bitches (2.11% incidence) that underwent elective OHE during September to November 2013 and evaluated by histopathology examination. Data were evaluated by using descriptive statistics and chi-squared tests. Bitches were of crossbred background with average age 5 years (range 0.6–8.0 years) and most were nulliparous (69.7%) with no anamnesis of reproductive diseases (81.6%). Frequencies of proestrus, estrus, and diestrus were 42.1%, 6.6%, and 19.7%, respectively. The presence of mammary gland masses (5.3%) significantly correlated with histopathologic findings in ovaries and age of the bitch (p < 0.05). Predominant uterine histopathologies included cystic endometrial hyperplasia, periglandular fibrosis, lymphoplasmocytary endometritis, and adenomyosis (19.7%, 14.5%, 4.0%, and 2.6%, respectively). In ovaries, hyperplasia of rete ovarii, follicular cysts, oophoritis, adenoma of the rete ovarii, cysts of superficial structures, and granulosa cell tumors (10.5%, 10.5%, 7.9%, 4.0%, 2.6%, and 2.6%, respectively) were observed. The results reveal the presence of subclinical pathologies in healthy bitches, suggesting that OHE at an early age is beneficial for prevention of reproductive pathologies.
Keywords: canine neoplastic disease, canine ovarian pathology, canine uterine pathology, cystic endometrial hyperplasia

© 2017 The Korean Society of Veterinary Science.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.