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J Vet Sci 2017; 18(3): 415-417  https://doi.org/10.4142/jvs.2017.18.3.415
Clinical application of quantitative computed tomography in osteogenesis imperfecta-suspected cat
Sungjun Won1,3, Woo-jo Chung2, Junghee Yoon3,*
1Irion Animal Hospital, Seoul 06015, Korea
2Ray Veterinary Medical Center, Seoul 06280, Korea
3College of Veterinary Medicine and the Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea
Correspondence to: Junghee Yoon
Tel: +82-2-880-1265; Fax: +82-2-876-8662; E-mail: heeyoon@snu.ac.kr
Received: June 2, 2016; Revised: October 4, 2016; Accepted: November 23, 2016; Published online: September 30, 2017.
Abstract
One-year-old male Persian cat presented with multiple fractures and no known traumatic history. Marked decrease of bone radiopacity and thin cortices of all long bones were identified on radiography. Tentative diagnosis was osteogenesis imperfecta, a congenital disorder characterized by fragile bone. To determine bone mineral density (BMD), quantitative computed tomography (QCT) was performed. The QCT results revealed a mean trabecular BMD of vertebral bodies of 149.9 ± 86.5 mg/cm3. After bisphosphonate therapy, BMD of the same site increased significantly (218.5 ± 117.1 mg/cm3, p < 0.05). QCT was a useful diagnostic tool to diagnose osteopenia and quantify response to medical treatment.
Keywords: cats, metabolic bone diseases, osteogenesis imperfecta, quantitative computed tomography


© 2017 The Korean Society of Veterinary Science.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.