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Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
Hanqin Shen , Xiangcong Liu, Pengfei Zhang, Lei Wang, Yanling Liu, Leyi Zhang, Pengshuai Liang, Changxu Song*
College of Animal Science & National Engineering Center for Swine Breeding Industry, South China Agriculture University, Guangzhou 510642, China
Correspondence to: Tel: +86-13829723528; Fax: +86-2085282651; E-mail: cxsong2004@163.com
Received: August 21, 2017; Revised: December 1, 2017; Accepted: December 26, 2017; Published online: December 28, 2017.
Abstract
Recently, a novel atypical porcine pestivirus (APPV) was discovered in pig. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor (CT) from China. The open reading frame of these two strains shared 83.5% nucleotide identity. Phylogenetically, the APPV strains were divided into two groups and GZ01 belonged to Group I, while GD-SD belonged to Group II. High viral load was detected in the cerebellum (Cq〈26). Further studies should be carried out to thoroughly understanding of congenital tremors causing by APPV.
Keywords: Atypical porcine pestivirus; Congenital tremor; Virus characterization


© 2017 The Korean Society of Veterinary Science.