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Novel reassortants of clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses possessing genetic heterogeneity in Republic of Korea in late 2017
Yu-Na Lee, Sun-Ha Cheon, Soo-Jeong Kye, Eun-Kyoung Lee, Mingeun Sagong, Gyeong-Beom Heo, Yong-Myung Kang, Hyun-Kyu Cho, Yong-Joo Kim, Hyun-mi Kang, Myoung-Heon Lee, Youn-Jeong Lee*
Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea
Correspondence to: Tel: +82-54-912-0968; Fax: +82-54-912-0977; E-mail: leeyj700@korea.kr
Received: June 22, 2018; Revised: August 10, 2018; Accepted: August 15, 2018; Published online: August 30, 2018.
Abstract
Novel H5N6 highly pathogenic avian influenza viruses (HPAIVs) were isolated from duck farms and migratory bird habitats in South Korea in November–December 2017. Genetic analysis demonstrated that at least two genotypes of H5N6 were generated through reassortment between clade 2.3.4.4 H5N8 HPAIVs and Eurasian low pathogenic avian influenza virus in migratory birds in late 2017, suggesting frequent reassortment of clade 2.3.4.4 H5 HPAIVs, and highlighting the need for systematic surveillance in Eurasian breeding grounds.
Keywords: highly pathogenic avian influenza; H5N6; H5N8; clade 2.3.4.4; reassortment


© 2018 The Korean Society of Veterinary Science.