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Corneoconjunctival manifestations of lymphoma in three dogs
Seonmi Kang1, Manbok Jeong2, Kangmoon Seo1,*
1Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea
2I Animal Medical Center, 779, Sosa-ro, Bucheon-si, Gyeonggi-do, 14427, Republic of Korea
Correspondence to: Tel: +82-2-880-1258; Fax: +82-2-883-8651; E-mail: kmseo@snu.ac.kr
Received: August 24, 2018; Revised: September 29, 2018; Accepted: October 10, 2018; Published online: November 26, 2018.
An 8-year-old Shih Tzu, a 5-year-old Maltese, and a 10-year-old Maltese presented with conjunctival hyperemia and peripheral corneal edema. Severe conjunctival thickening with varying degrees of corneal extension were observed. Cytological examination showed many large lymphocytes with malignant changes in the conjunctiva and were consistent with findings in fine-needle aspiration samples taken from the regional lymph nodes. They were diagnosed as having stage V multicentric lymphoma. When conjunctival thickening is observed in canine patients with multicentric lymphoma, conjunctival metastasis with infiltration of neoplastic lymphoid cells should be included in the differential diagnosis.
Keywords: Canine, Conjunctiva, Cornea, Multicentric lymphoma, Uvea

© 2018 The Korean Society of Veterinary Science.